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Fred Gage
Affiliation: Salk
Adjunct professor of Biology
gage@salk.edu
Phone: (858)453-4100Biography
Dr. Gage recieved his B.S. degree from The University of Florida and his Ph.D., from The Johns Hopkins University. Throughout his distinguished career, he recieved the Charles A. Dana Award for Pioneering Achievements in Health and Education in 1993, the Christopher Reeve Research Medal in 1997, and the Max Planck Research Prize in 1999. In 2003 he was inducted into the National Academy of Sciences.
Research Summary
Fred H. Gage, a professor in the Laboratory of Genetics, concentrates on the adult central nervous system and the unexpected plasticity and adaptability that remains throughout the life of all mammals. His work may lead to methods of replacing brain tissue lost to stroke or Alzheimer’s disease and repairing spinal cords damaged by trauma. Gage’s lab showed that, contrary to years of dogma, human beings are capable of growing new nerve cells throughout life. Small populations of immature nerve cells are found in the adult mammalian brain, and Gage is working to understand how these cells can be induced to become mature nerve cells. Gage’s team is investigating how such cells can be transplanted back to the brain and spinal cord. They showed that physical exercise can enhance the growth of new brain cells and are examining the underlying molecular mechanisms, work that may lead to new therapeutics for neurodegenerative conditions.
References
©2008 UCSD/Burnham Molecular Pathology Graduate Program