Histology

Units: 2
Quarter: Winter
Location: Garren Auditorium, BSB
Time: Thursday 8:00-12:00 Noon

The knowledge derived from images is fundamentally different from the knowledge derived from words. Learning how to read images is not merely an aesthetic luxury; it is a skill required of all physicians, one that can be developed with the same intensity and scholarly, analytic rigor as learning how to read numerical data in order to derive confidence intervals, and correlation coefficients.

This course presents the microscopic anatomy which comprises the structural basis of normal physiology. Such knowledge is essential for understanding disease mechanisms in terms of altered structure and function of the human body. Students are expected to identify the specialized cells, tissue and organs, and understand the structural basis of their function. Emphasis is placed on microscopic study conducted in small groups in laboratories under close supervision by the faculty and supplemented with MedPics, a computer-assisted image bank. Discussions will include drug mechanisms and some review of anatomy and physiology.

Objective:
The overall objective of the histology course is to help you acquire knowledge of normal histology. This is essential for understanding pathology where altered structure and function of diseased cells, tissues and organs are studied. In order to facilitate your study, specific learning objectives are described in each section of the course syllabus. The course provides a solid foundation for molecular biologists interested in the impact of gene ablation or transgene expression on animal development, for those interested in producing or using animal models of disease and for those who foresee themselves wanting to interpret the impact of therapeutics at the tissue level.

Student Priorities:
Up to 12 students from the Biomedical Sciences Program will be permitted to attend. The core student body are approximately 45 third year students in the School of Pharmacology. Priority will be given to Molecular Pathology track students in the BMS program, although we do not foresee space being an issue. Students designating themselves within the Molecular Pathology track may use this course as the second Winter quarter elective during first year training. BMS students in any year of training may take this class.

Students will need keys to the microscope labs. These are provided by Andrea Mondragon (amondragon@ucsd.edu; extension x46614 or at 822-6530). Andrea is located in the BSB room 1100. There is a key deposit required.

Lecture #1 Introduction to Epithelial and Connective Tissues, A. Mizisin, Ph.D

Lab Use of Microscope, Epithelial and Connective Tissues, Staff

Lecture #2 Bone and Cartilage, P. Haghighi, M.D.

Lab Bone and Cartilage, Staff

Lecture #3 Muscle Tissue and Cardiovascular System, Nigel Calcutt, Ph.D.

Lab Muscle Tissue and Cardiovascular System, Staff

Lecture #4 Lymphoid System, S. Baird, M.D.

Lab Lymphoid System, Staff

Lecture #5 Respiratory and Integumentary Systems, Andrew Mizisin, M.D.

Lab Respiratory and Integumentary Systems, Staff

Lecture #6 Accessory Digestive Glands, K. MIyai, M.D., Ph.D. / Endocrine System, A. Mizisin, Ph.D.

Lab Accessory Digestive Glands and Endocrine System, Staff

Lecture #7 Urinary System, A. Mizisin, Ph.D. / Male Reproductive System, N. Calcutt, Ph.D.

Lab Urinary and Male Reproductive Systems, Staff

Lecture #8 Introduction to Epithelial and Connective Tissues, A. Mizisin, Ph.D

Lab Use of Microscope, Epithelial and Connective Tissues, Staff

Lecture #9 Female Reproductive System, O.Mathieu-Costello, Ph.D.

Lab Female Reproductive System, Staff

HISTOLOGY REVIEW

FINAL EXAM

Training for Careers in Biomedical Research

Histology

Training for Careers in
Biomedical Research