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Mechanisms of Neurological Disease
PATH220

Units: 4
Quarter: Winter
Location: 205
Monday and Thursday
Time: 2 - 3:30 PM

The course covers the molecular and structural basis ofneurodegenerative diseases. Emphasis is placed on both the underlying mechanisms and potential avenues for therapeutic intervention.
Course goals are to develop skills in critical reading, analysis, presentation and creative hypothesis formulation using nineneurological diseases as a knowledge base (1 lecture and 1
discussion session each). Passing requirements are full attendance, participation and an oral presentation.

COURSE DIRECTOR: Nigel Calcutt


CONTACT: Nigel Calcutt at ncalcutt@ucsd.edu or 858-534-5331

Block Month Date Faculty Subject
Structure and Function

 
1. January 3 Andrew Mizisin (Block Leader) Neuroanatomy/Histology
2. January 6 Joan Heller Brown CNS transmitters
3. January 10 Charles Stevens Synaptic Physiology
4. January 13 Mizisin/Brown DISCUSSION
CNS Pharmacology        
5. January 17 Joan Heller Brown (Block Leader) Therapy of Psychiatric Diseases
6. January 20 Ron Kuczenski Methamphetamine
7. January 24 Stuart Lipton Excitotoxicity and Neuroprotective Drug Design
8. January 27 Brown/Calcutt STUDENT PRESENTATION I
Muscle and Nerve        
9. January 31 Nigel Calcutt (Block Leader) Peripheral Neuropathy
10. February 3 Palmer Taylor Drug Action at the Neuromuscular Junction
11. February 7 Diane Shelton Muscular Dystrophies & Myasthenia Gravis
12. February 10 Calcutt/Shelton STUDENT PRESENTATION II
CNS Processing        
13.    February 14 Martin Marsala Spinal Cord Injuries and Repair by Stem Cells
14. February 17 Tony Yaksh (Block Leader)

Neuropathic Pain
15. February 21 Tony Yaksh Treating Neuropathic Pain
16. February 24 Yaksh/Calcutt STUDENT PRESENTATION III
CNS Neurodegeneration        
17. February 28 Eliezer Masliah Alzheimers Disease
18. March 3 Katerina Akassoglou Multiple Sclerosis
19. March 7 Christina Sigurdson Prion Disease
20. March 10 Brown/Muotri THERAPEUTIC CASE STUDIES
21. March 14 TBD PRESENTATION IV
22. March 17 TBD PRESENTATION V

Notes:

Class mechanics and evaluation methods will be announced shortly before the course begins.

 

Questions or comments about the program?
©2008 UCSD/Burnham Molecular Pathology Graduate Program