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Units: 4 Modern Methods in Molecular Pathology
Quarter: Au
Location:
Time:
This class surveys the major methods used to approach molecular questions in basic research, and illustrates how these methods are used in the investigations into human disease that are performed in the laboratories of participating faculty. Understanding these techniques provides the foundation that students will use to then construct their own investigations into research questions--a process they will later use in classes, in their minor proposition, and throughout their thesis research.
Date
Day
Lecture Topic
Speaker/Lecture PDF
Supplements
9/20 WED Protein Purification Strategies - Still Critical in the Age of Molecular Biology This class will meet in the Leichtag Building, room 2a05 from 1:00 to 3:00. Note time change! Dzung Le 9/22 FRI DNA cloning Basics Mark Kamps 9/27 WED Fluorescence Probes in Localizing Proteins and Signal Transduction Roger Tsien, Part 2 9/29 FRI High Through-Put Microscopy and Applications in Cancer Research
Jeff Price 10/4 WED Electron Microscopy & Immunocytochemistry Marilyn Farquhar 10/6 FRI Electron Microscopy & Immunocytochemistry
Lab SessionMarilyn Farquhar 10/11 WED Microinjection; 3-D Confocal & Deconvolution Microscopy Jim Feramisco Sup 10/13 FRI Microinjection; 3-D Confocal & Deconvolution Microscopy, Lab Session Jim Feramisco 10/18 WED Proteinomics Tomas Mustelin 10/20 FRI Designing Inhibitors to Study Protein Function and to Discover Novel Therapeutics Ziwei Huang Sup 10/25 WED Protein Domains and Crystallographic Analysis No Homework will be assigned at this session due to Histology Exam October 26. Robert Liddington 10/27 FRI RNA Interference (RNAi) as a Research Tool Frances Gillin 11/1 WED GenBank & National Center for Biotechnology Information for Analysis of DNA Sequences & Protein Structures Guy Salvesen 11/3 FRI Retroviral Vectors in Biomedical Research Mark Kamps Verma 11/8 WED Promoter Analysis, Chromatin Immunoprecipitation, and Lentiviral Vectors Bruce Torbett Paper 2 11/10 FRI HOLIDAY 11/15 WED Stem Cells: Models for Differentiation and Therapeutic Tools Evan Snyder S1, S2, S3 11/17 FRI Shedding Light on Stem Cell Biology with Lentiviral Fluorescent Reporters Alexy Terskikh 11/17 FRI Functional Genomic Approaches, 1:30-3:30 in Leichtag 205 Nicolas Webster 11/22 WED Complete & Cell-type Specific Gene Elimination in Mice: Tools for Assessing Protein Function Gen-Sheng Feng 11/24 FRI THANKSGIVING HOLIDAY 11/29 WED Identifying Protein-Protein Interactions Using Yeast 2-Hybrid Dwayne Stupack Paper 2 12/1 FRI Laser-capture Microscopy and Whole Animal Imaging Kersi Pestonjamasp 12/6 WED Using Zebrafish Genetics and Morpholino Oligonucleotides to Approach Cancer Biology Richard Klemke 12/8 FRI Bacterial Virulence Factors-Discovery, Function, & Molecular Characterization Turn in last homework. No homework for this session. Victor Nizet 12/12 TUE REMEMBER YOUR REVIEW SESSION FOR HISTOLOGY! 12/14 THU REMEMBER YOUR HISTOLOGY EXAM!
©2008 UCSD/Burnham Molecular Pathology Graduate Program